ANDARINE (S4)

S4 (Andarine) – 1000mg powder

Due to the difficulty of researching with liquids, dosing/crystalization and user feedback.  We have decided to switch to powder

 SARMS.

(2S)-3-(4-acetamido-phenoxy)-2-hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-propionamide

S4 (Andarine) is an investigational selective androgen receptor modulator (SARM) developed by GTX.INC for treatment of conditions such as muscle wasting, osteoporosis and benign prostatic hypertrophy, us the non-steroidal androgen antagonist bicalutamide as a lead compound.

Andarine is an orally active partial agonist for androgen receptors. In an animal model of benign prostatic hypertrophy, andarine was shown to reduce prostate weight with similar efficacy to finasteride, but without producing any reduction in muscle mass or anti-androgenic side effects.This suggests that it is able to competitively block binding of dihydrostestosterone to its receptor targets in the prostate gland, but its partial agonist effects at androgen receptors prevent the side effects associated with the anti-androgenic drugs traditionally used for treatment of BPH.

S-4 (3 mg/kg/day) was also able to restore skeletal muscle (i.e., soleus muscle) and strength in castrated rats, important and applicable for the treatment of muscle wasting and male HRT.

A 120-day study comparing SARM S-4 and dihydrotestosterone (DHT) treatment in ovariectomized rats demonstrated that S-4 was able to maintain bone mass and bone strength to the levels of intact controls and exhibited greater efficacy than DHT.

Testosterone shows a very similar increase in muscle and prostate growth in a dose dependent manner where S-4 shows a great increase in muscle growth with prostate growth staying largely uniform.

S-4 also demonstrated the ability to improve skeletal muscle strength, increase lean body mass (LBM), reduce body fat, and prevent bone loss.

This article is intended for educational / informational purposes only. THIS PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only.

Andarine, also known as S4, is a selective androgen receptor modulator (SARM) that is commonly used in the fitness and bodybuilding community as a performance-enhancing drug. It works by selectively binding to androgen receptors in the body, which can help increase muscle mass and strength, improve endurance, and reduce recovery time.

One of the unique features of Andarine is its ability to selectively bind to androgen receptors in the muscles and bones, while avoiding binding to androgen receptors in other parts of the body. This can help reduce the risk of negative side effects, such as prostate enlargement, that are commonly associated with anabolic steroids.

Despite its potential benefits, Andarine is not approved for human use and its long-term effects on the body are not well understood. Some animal studies have suggested that it may have negative effects on vision, including a yellowish tint and difficulty adjusting to low light conditions. However, more research is needed to fully understand these potential risks.

Additionally, Andarine is banned by the World Anti-Doping Agency (WADA) as a performance-enhancing drug, and its use in competitive sports is strictly prohibited. Athletes who test positive for Andarine may face serious consequences, including suspension and loss of eligibility to compete.

It is important to note that individuals considering the use of Andarine should consult with a healthcare professional before beginning use. They should also be aware of the potential risks associated with the drug, including negative effects on vision and the risk of suspension from competition.

In summary, Andarine is a selective androgen receptor modulator (SARM) that is commonly used in the fitness and bodybuilding community as a performance-enhancing drug. While it has potential benefits for increasing muscle mass and strength, its long-term effects on the body are not well understood and there are potential risks, including negative effects on vision. Its use in competitive sports is strictly prohibited, and individuals should consult with a healthcare professional before considering its use.